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          System Message

          OKCancel
          LOADING ...
          See other TP53 SIRNA Assays ›
          Gene Symbol:
          TP53
          Gene Name:
          tumor protein p53
          Gene Aliases:
          BCC7, LFS1, P53, TRP53
          Chromosome Location:
          Chr.17: 7668402 - 7687550 on Build GRCh38
          UniGene ID:
          Hs.437460
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s536422

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
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          siRNA Details

          Gene Symbol: TP53
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000546.5 NP_000537.3 6 828
          NM_001126112.2 NP_001119584.1 6 825
          NM_001126113.2 NP_001119585.1 6 828
          NM_001126114.2 NP_001119586.1 6 828
          NM_001126115.1 NP_001119587.1 2 508
          NM_001126116.1 NP_001119588.1 2 508
          NM_001126117.1 NP_001119589.1 2 508
          NM_001126118.1 NP_001119590.1 5 945
          NM_001276695.1 NP_001263624.1 6 828
          NM_001276696.1 NP_001263625.1 6 828
          NM_001276697.1 NP_001263626.1 2 508
          NM_001276698.1 NP_001263627.1 2 508
          NM_001276699.1 NP_001263628.1 2 508
          NM_001276760.1 NP_001263689.1 6 828
          NM_001276761.1 NP_001263690.1 6 825
          GenBank mRNA AB082923.1 - 6 689
          AF307851.1 - 6 761
          AK225838.1 - 6 766
          AK297462.1 - 7 693
          AK297927.1 - 7 738
          AK303277.1 - 5 884
          AK312568.1 - 6 770
          AM076970.1 - 5 593
          AM076971.1 - 5 626
          AM076972.1 - 5 626
          AY429684.1 - 5 626
          BC003596.1 - 6 746 3544714
          BT019622.1 - 5 626
          DQ186648.1 - 6 758
          DQ186649.1 - 6 758
          DQ186650.1 - 2 504
          DQ186651.1 - 2 504
          DQ186652.1 - 2 504
          DQ191317.1 - 6 815
          DQ263704.1 - 5 626
          DQ286964.1 - 6 760
          DQ648884.1 - 5 426
          DQ648885.1 - 3 302
          EF101867.1 - 5 593
          EF101868.1 - 5 626
          EF101869.1 - 5 626
          FJ207420.1 - 6 761
          JN214348.1 - 5 671
          JN601513.1 - 5 626
          JN601514.1 - 5 626
          JN601515.1 - 5 626
          JN601516.1 - 6 600
          JN900492.1 - 5 934
          JQ026207.1 - 5 616
          JQ026208.1 - 5 621
          JQ026209.1 - 5 626
          JQ026210.1 - 5 626
          JQ694049.1 - 5 649
          JQ694050.1 - 5 649
          JQ694051.1 - 5 649
          KC820708.1 - 2 121
          KC820709.1 - 2 121
          KC820710.1 - 2 121
          KC820711.1 - 2 121
          KC820712.1 - 2 121
          KC820713.1 - 2 121
          KC820714.1 - 2 121
          KC820715.1 - 2 121
          KC820716.1 - 2 121
          KC820717.1 - 2 121
          KC820718.1 - 2 121
          KC820719.1 - 2 121
          KC820720.1 - 2 121
          KC820721.1 - 2 121
          KC820722.1 - 2 121
          KC820723.1 - 2 121
          KC820724.1 - 2 121
          KC820725.1 - 2 121
          KC820726.1 - 2 121
          KC820727.1 - 2 121
          KC820728.1 - 2 121
          KC820729.1 - 2 121
          KC820730.1 - 2 121
          KC820731.1 - 2 121
          KC820732.1 - 2 121
          KC820733.1 - 2 121
          KC820734.1 - 2 121
          KC820735.1 - 2 121
          KC820736.1 - 2 121
          KC820737.1 - 2 121
          KC820738.1 - 2 121
          KC820739.1 - 2 121
          KC820740.1 - 2 121
          KC820741.1 - 2 121
          KC820742.1 - 2 121
          KC820743.1 - 2 121
          KC820744.1 - 2 121
          KC820745.1 - 2 121
          KC820746.1 - 2 121
          KC820747.1 - 2 121
          KC820748.1 - 2 121
          KC820749.1 - 2 121
          KC820750.1 - 2 121
          KC820751.1 - 2 121
          KC820752.1 - 2 121
          KC820753.1 - 2 121
          KC820754.1 - 2 121
          KC820755.1 - 2 121
          KC820756.1 - 2 121
          KC820757.1 - 2 121
          KC820758.1 - 2 121
          KC820760.1 - 2 121
          KC820761.1 - 2 121
          KC820762.1 - 2 121
          KC820763.1 - 2 121
          KC820764.1 - 2 121
          KC820765.1 - 2 121
          KC820766.1 - 2 121
          KC820767.1 - 2 121
          KC820768.1 - 2 121
          KC820769.1 - 2 121
          KC820770.1 - 2 121
          KC820771.1 - 2 121
          KC820772.1 - 2 121
          KC820773.1 - 2 121
          KC820774.1 - 2 121
          KC820775.1 - 2 121
          KC820776.1 - 2 121
          KC820777.1 - 2 121
          KC820778.1 - 2 121
          KC820779.1 - 2 121
          KC820780.1 - 2 121
          KC820781.1 - 2 121
          KC820782.1 - 2 121
          KC820783.1 - 2 121
          KC820784.1 - 2 121
          KC820785.1 - 2 121
          KC820786.1 - 2 121
          M14694.1 - 6 751
          M14695.1 - 6 747
          X01405.1 - 3 327
          X02469.1 - 6 761
          X60010.1 - 5 625
          X60011.1 - 5 626
          X60012.1 - 5 626
          X60013.1 - 5 626
          X60014.1 - 5 626
          X60015.1 - 5 626
          X60016.1 - 5 626
          X60017.1 - 5 626
          X60018.1 - 5 626
          X60019.1 - 5 626
          X60020.1 - 5 626

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: XM_003749209.

          Panther Classification:

          Molecular Function -

          P53-like transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          DNA strand renaturation
          base-excision repair
          nucleotide-excision repair
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          protein complex assembly
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          ER overload response
          cell cycle arrest
          Ras protein signal transduction
          multicellular organism development
          cell aging
          protein localization
          cell proliferation
          negative regulation of cell proliferation
          determination of adult lifespan
          response to X-ray
          response to gamma radiation
          positive regulation of gene expression
          viral process
          protein sumoylation
          cell differentiation
          negative regulation of cell growth
          DNA damage response, signal transduction by p53 class mediator
          positive regulation of histone deacetylation
          chromatin assembly
          mitotic G1 DNA damage checkpoint
          positive regulation of protein oligomerization
          cellular response to UV
          cellular response to drug
          cellular response to glucose starvation
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          entrainment of circadian clock by photoperiod
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of neuron apoptotic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          response to antibiotic
          positive regulation of protein export from nucleus
          regulation of mitochondrial membrane permeability
          negative regulation of fibroblast proliferation
          circadian behavior
          positive regulation of peptidyl-tyrosine phosphorylation
          negative regulation of helicase activity
          protein tetramerization
          negative regulation of telomerase activity
          positive regulation of thymocyte apoptotic process
          positive regulation of cell cycle arrest
          cellular response to hypoxia
          cellular response to ionizing radiation
          intrinsic apoptotic signaling pathway by p53 class mediator
          positive regulation of release of cytochrome c from mitochondria
          replicative senescence
          oxidative stress-induced premature senescence
          intrinsic apoptotic signaling pathway
          oligodendrocyte apoptotic process
          positive regulation of execution phase of apoptosis
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of signal transduction by p53 class mediator
          regulation of cell cycle G2/M phase transition
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          positive regulation of reactive oxygen species metabolic process
          positive regulation of intrinsic apoptotic signaling pathway
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          protease binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          copper ion binding
          protein binding
          ATP binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          protein kinase binding
          protein phosphatase binding
          receptor tyrosine kinase binding
          ubiquitin protein ligase binding
          histone acetyltransferase binding
          identical protein binding
          sequence-specific DNA binding
          protein self-association
          transcription regulatory region DNA binding
          protein heterodimerization activity
          protein N-terminus binding
          chaperone binding
          protein phosphatase 2A binding

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          Host server : magellan-search-blue-555ccb4fbd-9p96w:80/100.66.78.180:80.
          git-commit: 75f0c7d4cb44686da2af39b21f2e6446a20282e2
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-2025.12.99-1.0