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          System Message

          OKCancel
          LOADING ...
          See other PTEN SIRNA Assays ›
          Gene Symbol:
          PTEN PTENP1
          Gene Name:
          phosphatase and tensin homolog
          phosphatase and tensin homolog pseudogene 1
          Gene Aliases:
          10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1
          PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN
          Chromosome Location:
          Chr.10: 87863438 - 87971930 on Build GRCh38
          Chromosome Location:
          Chr.9: 33673504 - 33677420 on Build GRCh38
          UniGene ID:
          Hs.500466
          Hs.493716
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          -
          siRNA ID s61222

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PTEN
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000314.6 NP_000305.3 8 1953
          NM_001304717.2 NP_001291646.2 8 1953
          NM_001304718.1 NP_001291647.1 8 2067
          GenBank mRNA AK313581.1 - 8 1114
          BC005821.2 - 8 1758 3937787
          CR450306.1 - 8 922
          JF268690.1 - 8 1085
          KJ534922.1 - 8 922
          U92436.1 - 8 1956
          U93051.1 - 8 922
          U96180.1 - 8 1726
          Gene Symbol: PTENP1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NR_023917.1 1 1691
          GenBank mRNA AF017999.1 - 1 922
          AF019083.1 - 1 922
          BC038293.2 - 1 1175

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_008960, AK076980, AK138025, U92437, AK030750, and others.

          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          regulation of cyclin-dependent protein serine/threonine kinase activity
          angiogenesis
          negative regulation of protein phosphorylation
          regulation of B cell apoptotic process
          protein dephosphorylation
          phosphatidylinositol biosynthetic process
          apoptotic process
          neuron-neuron synaptic transmission
          synapse assembly
          central nervous system development
          heart development
          aging
          response to nutrient
          learning or memory
          memory
          locomotory behavior
          cell proliferation
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          response to glucose
          response to zinc ion
          regulation of neuron projection development
          negative regulation of phosphatidylinositol 3-kinase signaling
          cell migration
          dentate gyrus development
          central nervous system neuron axonogenesis
          negative regulation of cell migration
          adult behavior
          negative regulation of myelination
          regulation of protein stability
          negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
          regulation of synaptic transmission, GABAergic
          central nervous system myelin maintenance
          response to estradiol
          regulation of cellular component size
          regulation of myeloid cell apoptotic process
          response to ATP
          multicellular organismal response to stress
          social behavior
          peptidyl-tyrosine dephosphorylation
          response to drug
          maternal behavior
          negative regulation of apoptotic process
          protein kinase B signaling
          endothelial cell migration
          inositol phosphate metabolic process
          response to ethanol
          locomotor rhythm
          negative regulation of cell size
          negative regulation of organ growth
          response to arsenic-containing substance
          inositol phosphate dephosphorylation
          phosphatidylinositol dephosphorylation
          platelet-derived growth factor receptor signaling pathway
          phosphatidylinositol-mediated signaling
          regulation of axon regeneration
          cardiac muscle tissue development
          forebrain morphogenesis
          brain morphogenesis
          negative regulation of epithelial cell proliferation
          negative regulation of phagocytosis
          negative regulation of axonogenesis
          protein stabilization
          T cell receptor signaling pathway
          positive regulation of sequence-specific DNA binding transcription factor activity
          negative regulation of focal adhesion assembly
          negative regulation of protein kinase B signaling
          rhythmic synaptic transmission
          canonical Wnt signaling pathway
          synapse maturation
          prepulse inhibition
          male mating behavior
          long-term synaptic potentiation
          long term synaptic depression
          prostate gland growth
          dendritic spine morphogenesis
          negative regulation of dendritic spine morphogenesis
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of ERK1 and ERK2 cascade
          cellular response to hypoxia
          negative regulation of ribosome biogenesis
          negative regulation of cell aging
          negative regulation of excitatory postsynaptic potential
          presynaptic membrane assembly
          postsynaptic density assembly
          positive regulation of TRAIL-activated apoptotic signaling pathway
          positive regulation of ubiquitin protein ligase activity
          positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of G1/S transition of mitotic cell cycle
          positive regulation of excitatory postsynaptic potential
          negative regulation of synaptic vesicle clustering
          magnesium ion binding
          phosphatidylinositol-3-phosphatase activity
          phosphoprotein phosphatase activity
          protein serine/threonine phosphatase activity
          protein tyrosine phosphatase activity
          platelet-derived growth factor receptor binding
          protein binding
          protein tyrosine/serine/threonine phosphatase activity
          lipid binding
          anaphase-promoting complex binding
          phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
          enzyme binding
          protein kinase binding
          PDZ domain binding
          identical protein binding
          inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
          phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity

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