Hamburger Menu Button
Thermo Fisher Scientific Logo
登录
没有账号?建立账号 注册
  • 产品
    • 抗体
    • 引物合成
    • GeneArt Gene Synthesis Instant Designer
    • TaqMan Assay and Array Search
    • PCR 设备和耗材
    • 色谱柱和纯化柱
    • 实验室离心机
    • 分子生物学试剂和试剂盒
    • 实验室塑料耗材及用品
    • 查看所有产品分类
  • 应用和技术
    • 色谱
    • 细胞转染和培养
    • 实时荧光定量PCR
    • 质谱
    • 实验室塑料耗材及用品
    • 电子显微镜
    • 蛋白质生物学
    • PCR
    • RNAi
    • 环境
    • 查看所有应用和技术
  • 服务
    • 定制服务
    • 企业级实验室信息化服务
    • 企业服务
    • 金融&租赁服务
    • 仪器服务
    • OEM和商业供应
    • 培训服务
    • 360° CDMO 和 CRO 服务
    • CDMO 服务
    • 临床试验 CRO 服务
    • 查看所有帮助和支持
  • 帮助和支持
    • 学习中心
    • 联系我们
    • 更改国家或地区
    • 查看所有帮助和支持
  • 热门产品
    • TaqMan Real-Time PCR Assays
      TaqMan 实时荧光定量 PCR 试剂盒
    • Antibodies
      抗体
    • Oligos, Primers & Probes
      寡核苷酸、引物、探针
    • GeneArt Gene Synthesis
      GeneArt 基因合成
    • Cell Culture Plastics
      细胞培养耗材
  • 联系我们
  • 货号直购
  • 订单查询
  • 查找文件&证书
Thermo Fisher Scientific Logo

Search

搜索全部或下列指定分类
Search button
          • 联系我们
          • 货号直购
          • 登录
            登录
            没有账号?建立账号 注册
            • 我的账号
            • 订单
            • 账单及发票查询
            • 定制产品及项目
          This product has been added to your favorites list. Go to My Favorites

          System Message

          OKCancel
          LOADING ...
          See other PARK2 SIRNA Assays ›
          Gene Symbol:
          Park2
          Gene Name:
          Parkinson disease (autosomal recessive, juvenile) 2, parkin
          Gene Aliases:
          PRKN
          Chromosome Location:
          Chr.17: 10840384 - 12063370 on Build GRCm38
          UniGene ID:
          Mm.311110
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID s78529

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price 5,354.00
          Your Price
          Online offer:
          5354.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
          ×
          Back To Top

          siRNA Details

          Gene Symbol: Park2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_016694.3 NP_057903.1 2 188
          GenBank mRNA AB019558.1 - 2 159
          AF250293.1 - 2 188
          AF250294.1 - 2 188
          AF250295.1 - 2 188
          BC113204.1 - 2 171 40047891
          FJ555555.1 - 1 159
          FJ555556.1 - 2 159
          FJ555557.1 - 2 159
          GU272056.1 - 1 159

          Back To Top

          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_020093, GU322363, AB039878, AF168004, AF381280, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          protein polyubiquitination
          mitophagy
          negative regulation of protein phosphorylation
          synaptic transmission, dopaminergic
          startle response
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          protein monoubiquitination
          autophagy
          response to unfolded protein
          learning
          locomotory behavior
          adult locomotory behavior
          proteasomal protein catabolic process
          regulation of autophagy
          positive regulation of gene expression
          negative regulation of gene expression
          positive regulation of mitochondrial fusion
          regulation of mitochondrion organization
          protein ubiquitination
          protein metabolic process
          regulation of protein ubiquitination
          negative regulation of actin filament bundle assembly
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          negative regulation of glucokinase activity
          response to endoplasmic reticulum stress
          synaptic transmission, glutamatergic
          regulation of dopamine metabolic process
          norepinephrine metabolic process
          dopamine metabolic process
          protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of DNA binding
          negative regulation of neuron apoptotic process
          cellular protein catabolic process
          negative regulation by host of viral genome replication
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of insulin secretion
          regulation of neurotransmitter secretion
          modulation of synaptic transmission
          protein stabilization
          positive regulation of neurotransmitter uptake
          dopamine uptake involved in synaptic transmission
          mitochondrion localization
          protein autoubiquitination
          regulation of mitochondrial membrane potential
          negative regulation of cell death
          protein K63-linked ubiquitination
          protein localization to mitochondrion
          aggresome assembly
          protein K48-linked ubiquitination
          protein K11-linked ubiquitination
          protein K6-linked ubiquitination
          negative regulation of release of cytochrome c from mitochondria
          cellular response to toxic substance
          mitophagy in response to mitochondrial depolarization
          regulation of cellular response to oxidative stress
          negative regulation of neuron death
          positive regulation of proteasomal protein catabolic process
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          negative regulation of primary amine oxidase activity
          positive regulation of protein linear polyubiquitination
          negative regulation of oxidative stress-induced neuron death
          regulation of protein targeting to mitochondrion
          positive regulation of tumor necrosis factor-mediated signaling pathway
          negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
          positive regulation of dendrite extension
          negative regulation of spontaneous neurotransmitter secretion
          regulation of reactive oxygen species metabolic process
          negative regulation of reactive oxygen species metabolic process
          G-protein coupled receptor binding
          actin binding
          ubiquitin-protein transferase activity
          protein binding
          zinc ion binding
          UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
          tubulin binding
          ligase activity
          ribosomal S6-glutamic acid ligase activity
          enzyme binding
          kinase binding
          protein kinase binding
          PDZ domain binding
          Hsp70 protein binding
          heat shock protein binding
          ubiquitin conjugating enzyme binding
          ubiquitin protein ligase binding
          protein complex binding
          identical protein binding
          histone deacetylase binding
          ubiquitin binding
          phospholipase binding
          coenzyme F420-0 gamma-glutamyl ligase activity
          coenzyme F420-2 alpha-glutamyl ligase activity
          metal ion binding
          chaperone binding
          ubiquitin protein ligase activity
          protein-glycine ligase activity
          protein-glycine ligase activity, initiating
          protein-glycine ligase activity, elongating
          tubulin-glycine ligase activity
          protein-glutamic acid ligase activity
          tubulin-glutamic acid ligase activity
          cullin family protein binding
          ubiquitin-specific protease binding
          F-box domain binding

          Back To Top

          Related Products

          • Anti-GAPDH, Mouse Monoclonal 6C5
          • Anti-β-Actin, Mouse Monoclonal AC-15
          • TaqMan® Gene Expression Cells-to-CT™
          • Neon™ Transfection System 100 µL Kit
          • Lipofectamine™ RNAiMAX Transfection Reagent
          • Invivofectamine 2.0
          • Lipofectamine™ 2000 Transfection Reagent
          • Neon™ Transfection System
          订购 Plus Icon Minus Icon
          • 订单状态查询
          • 订单支持
          • 货号直购
          • 现货供应中心
          • 电子采购
          支持 Plus Icon Minus Icon
          • 帮助&支持
          • 联系我们 - 400 820 8982
          • 技术支持中心
          • 查找文件&证书
          • 报告网站问题
          资源 Plus Icon Minus Icon
          • 学习中心
          • 促销
          • 活动&研讨会
          • 社交媒体
          关于赛默飞 Plus Icon Minus Icon
          • 关于我们
          • 招聘 招聘
          • 投资者关系 投资者关系
          • 新闻 新闻
          • 社会责任 社会责任
          • 商标
          • 政策和通知
          品牌 Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Patheon
          • PPD
          • 服务条款
          • 隐私政策
          • 定价和运输保险政策
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          China flag icon
          China
          本网站销售的所有产品均不得用于人类或动物之临床诊断或治疗,仅可用于工业或者科研等非医疗目的。
             电子营业执照 | 经营证照公示 | ICP备案号:沪ICP备11003924号 | 沪公网安备 31011502006935号

          Your items have has been added!


          Host server : magellan-search-green-55658555d6-2l4dt:80/100.66.76.49:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline