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          System Message

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          LOADING ...
          See other MSH2 SIRNA Assays ›
          Gene Symbol:
          MSH2
          Gene Name:
          mutS homolog 2
          Gene Aliases:
          COCA1, FCC1, HNPCC, HNPCC1, LCFS2
          Chromosome Location:
          Chr.2: 47403067 - 47634501 on Build GRCh38
          UniGene ID:
          Hs.597656
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s8966

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: MSH2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000251.2 NP_000242.1 10 1691
          NM_001258281.1 NP_001245210.1 11 1507
          XM_005264332.3 XP_005264389.2 10 1638
          XM_011532867.1 XP_011531169.1 10 1638
          GenBank mRNA AK222860.1 - 10 1628
          AK223284.1 - 10 1601
          AK296831.1 - 9 1166
          AK297763.1 - 10 1394
          AK299667.1 - 9 1026
          AK304496.1 - 11 1507
          BC021566.1 - 10 1580 4110354
          BX649122.1 - 10 1586
          DQ648896.1 - 4 378
          L47574.1 - 10 1606
          L47575.1 - 10 1604
          L47576.1 - 10 1605
          L47577.1 - 10 1606
          L47578.1 - 10 1607
          L47579.1 - 10 1606
          L47580.1 - 10 1606
          L47581.1 - 10 1606
          L47582.1 - 10 1606
          L47583.1 - 10 1606
          U03911.1 - 10 1569
          U04045.1 - 10 1634

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          More Information


          Panther Classification:

          Molecular Function -

          DNA metabolism protein

          Gene Ontology Categories:

          Function(s) Process(es)

          meiotic mismatch repair
          in utero embryonic development
          oxidative phosphorylation
          DNA repair
          mismatch repair
          postreplication repair
          double-strand break repair
          meiotic gene conversion
          cell cycle arrest
          reciprocal meiotic recombination
          germ cell development
          determination of adult lifespan
          male gonad development
          response to X-ray
          response to UV-B
          somatic hypermutation of immunoglobulin genes
          somatic recombination of immunoglobulin gene segments
          B cell mediated immunity
          B cell differentiation
          intra-S DNA damage checkpoint
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          negative regulation of neuron apoptotic process
          maintenance of DNA repeat elements
          negative regulation of reciprocal meiotic recombination
          isotype switching
          negative regulation of DNA recombination
          positive regulation of helicase activity
          magnesium ion binding
          four-way junction DNA binding
          Y-form DNA binding
          heteroduplex DNA loop binding
          double-strand/single-strand DNA junction binding
          DNA binding
          double-stranded DNA binding
          single-stranded DNA binding
          protein binding
          ATP binding
          protein C-terminus binding
          ATPase activity
          centromeric DNA binding
          enzyme binding
          protein kinase binding
          mismatched DNA binding
          guanine/thymine mispair binding
          dinucleotide insertion or deletion binding
          single guanine insertion binding
          single thymine insertion binding
          dinucleotide repeat insertion binding
          oxidized purine DNA binding
          MutLalpha complex binding
          protein homodimerization activity
          ADP binding

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