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Invitrogen
Human ARTS Synthetic Peptide
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产品信息
PEP-0123
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 12 amino amino terminus of human ARTS.
PEP-0123 can be used as a blocking peptide with polyclonal antibody PA5-20001.
靶标信息
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; Bradeion beta; Brain protein H5; CE5B3 beta; Cell division control-related protein 2; cerebral protein 7; hCDCREL-2; Peanut-like protein 2; Septin-4; septin-M
基因别名: ARTS; BRADEION; C17orf47; CE5B3; H5; hCDCREL-2; hucep-7; MART; PNUTL2; SEP4; SEPT4; SEPTIN4
UniProt ID: (Human) O43236
Entrez Gene ID: (Human) 5414
