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Gibco
Human BMP-7 Recombinant Protein, PeproTech®
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产品信息
120-03P-10UG
应用
建议稀释比
已发表文章
产品规格
种属
Human
已发表种属
Human,
Mouse,
Rat
Expression System
CHO cells
氨基酸序列
MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
分子量
26.4 kDa
分类
Recombinant
类型
Protein
纯度
≥ 98% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
活性
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.02-0.04 ug/ml.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
120-03P-1MG will be provided as 10 x 100 µg (120-03P-100UG).
120-03P-500UG will be provided as 5 x 100 µg (120-03P-100UG).
Recombinant Recombinant Human BMP-7 has a calculated molecular weight of 26.4 kDa; however, due to glycosylation, the BMP-7 homodimer migrates at an apparent molecular weight of approximately 25-35 kDa by SDS-PAGE analysis under non-reducing conditions.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BMP; BMP-7; Bone morphogenetic protein; Bone morphogenetic protein 7; OP-1; Osteogenic protein 1; RP11-560A15.5
基因别名: BMP7; OP-1; OP1
UniProt ID: (Human) P18075
Entrez Gene ID: (Human) 655
