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Gibco
Human FRP-1 (soluble) Recombinant Protein, PeproTech®
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产品信息
120-29-20UG
应用
建议稀释比
已发表文章
产品规格
种属
Human
已发表种属
Human,
Mouse
Expression System
HeLa cells
氨基酸序列
SEYDYVSFQS DIGPYQSGRF YTKPPQCVDI PADLRLCHNV GYKKMVLPNL LEHETMAEVK QQASSWVPLL NKNCHAGTQV FLCSLFAPVC LDRPIYPCRW LCEAVRDSCE PVMQFFGFYW PEMLKCDKFP EGDVCIAMTP PNATEASKPQ GTTVCPPCDN ELKSEAIIEH LCASEFALRM KIKEVKKENG DKKIVPKKKK PLKLGPIKKK DLKKLVLYLK NGADCPCHQL DNLSHHFLIM GRKVKSQYLL TAIHKWDKKN KEFKNFMKKM KNHECPTFQS VFK
分子量
32.5 kDa
分类
Recombinant
类型
Protein
纯度
≥ 97% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
活性
Determined by its ability to inhibit BMP-2 proliferation effect of ATDC-5 cells. The expected ED50 is 0.3-0.5 ug/ml.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
Recombinant Human sFRP-1 is a glycosylated 283 amino acid protein containing a cysteine-rich Frizzled homologous domain. The calculated molecular weight of Recombinant Human sFRP-1 is 32.5 kDa.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: frizzled-related protein; FRP-1; SARP-2; Secreted apoptosis-related protein 2; Secreted frizzled-related protein 1; sFRP-1
基因别名: FRP; FRP-1; FRP1; FrzA; SARP2; SFRP1
UniProt ID: (Human) Q8N474
Entrez Gene ID: (Human) 6422
