Invitrogen

Human Factor X Native Protein

Name: Human Factor X Native Protein
Brand: Invitrogen
SKU: RP-43072

查看其他 (11) Factor X 蛋白

说明书

技术支持

说明书

技术支持

说明书

技术支持

产品信息

RP-43072

应用

建议稀释比

已发表文章

中和实验 (Neu)

Assay-dependent

产品规格

种属

Human

分子量

58.9 kDa

分类

Native

类型

Protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

10.6 mg/mL

纯化类型

SDS-PAGE

保存液

50% water with 50% glycerol

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

产品详细信息

RP-43072 contains native human Factor X protein purified from blood/plasma.

RP-43072 may be used as a positive control in many immunological assays.

The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.

This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

靶标信息

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。