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Recombinant Human Uteroglobin is a 16.1 kDa homodimeric protein consisting of 142 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: blastokinin; CC10; CCPBP; club cell 10 kDa secretory protein; Club cell phospholipid-binding protein; club cell protein 16; Club cells 10 kDa secretory protein; club secretory protein 16; SCGB1A1; Secretoglobin family 1A member 1; secretoglobin family 1A member 1 (uteroglobin) isoform SCGB1A1_1; secretoglobin family 1A member 1 (uteroglobin) isoform SCGB1A1_2; secretoglobin, family 1A, member 1 (uteroglobin); unnamed protein product; UP-1; Urinary protein 1; urine protein 1; Uteroglobin; Uteroglobin (club-cell specific 10-kD protein)
Gene Aliases: CC10; CC16; CCPBP; CCSP; SCGB1A1; UGB; UP-1; UP1
UniProt ID: (Human) P11684
Entrez Gene ID: (Human) 7356
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