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Gibco
Porcine IL-4, AOF Recombinant Protein
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产品信息
RP-87793
产品规格
种属
Pig
Expression System
E. coli
氨基酸序列
MHKCDITLQE IIKTLNILTA RKNSCMELPV TDVFAAPENT TEKETFCRAS TVLRHIYRHH TCMKSLLSGL DRNLSSMANM TCSVHEAKKS TLKDFLERLK TIMKEKYSKC
分子量
12.7 kDa
分类
Recombinant
类型
Protein
纯度
≥95% by SDS-Page
内毒素浓度
≤0.1 EU/µg
活性
ED50 ≤ 2 ng/mL; determined by the dose-dependent proliferation of TF-1 cells.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
10mM sodium phosphate, pH 7.5
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Animal Origin Free
Reconstitution: Sterile Water at 0.1 mg/mL
靶标信息
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell stimulatory factor 1; BSF-1; cytokine; H-IL-4; IL-4; ILN; Interleukin; Interleukin-4; Interleukin4; Lymphocyte stimulatory factor 1; M-IL-4; MGC79402
基因别名: IL4
UniProt ID: (Pig) Q04745
Entrez Gene ID: (Pig) 397225
