EphA3 Proteins

Protein Information

EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands and receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.

Synonyms

AW492086; Cek4; EK4; End3; EPH receptor A3; EPHA3; EPH-like kinase 4; Eph-like tyrosine kinase 1; Ephrin type-A receptor 3; ETK; ETK1; H TYRO4; Hek; Hek4; Human embryo kinase; human embryo kinase 1; I79_002835; Mek4; rEK4; testicular tissue protein Li 64; TYRO4; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor ETK1; tyrosine-protein kinase receptor REK4; tyrosine-protein kinase TYRO4