The IL-6 protein is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions.
PeproTech Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfe bond. PeproGMP IL-2 is commonly used in ex vivo cell therapy for the expansion of T and NK immune cell cultures.
The PeproTech Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml. Additional product information, specifications, handling and reconstitution information are provided on the...
Thrombopoietin (TPO) is a hematopoietic growth factor that stimulates the proliferation and maturation of megakaryocytes. The human TPO gene encodes for a 353 amino acid glycoprotein, which contains a 21 amino acid signal sequence, a 15 amino acid erythropoietin-like domain, and a highly...
The neuregulin/heregulin protein is a family of structurally-related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). The PeproTech Recombinant Human Heregulin beta-1 (HRG1-beta1 is a 7.
PeproTech Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml. Additional product information, specifications, handling and reconstitution information are provided on the Certificate of...
PeproTech Recombinant Human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues. PeproGMP IL-15 can be used with PeproGMP IL-7 in CTS NK-Xpander medium for natural killer (NK) cell differentiation from pluripotent stem cells. Reconstitute using sterile water (i.e.
The PDGF proteins are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The PeproTech Recombinant Human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two alpha-chains (250 total amino acids). Reconstitute using sterile water (i.e.
Flt3-Ligand (FLT3L) is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other...
Stem cell factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic stem cells (HSCs) and progenitors committed to the melanocyte and germ cell...
PeproTech Recombinant Human IL-7 is a 17.4 kDa protein containing 152 amino acid residues. PeproGMP IL-7 can be used with PeproGMP IL-15 in CTS NK-Xpander medium for natural killer (NK) cell differentiation from pluripotent stem cells. Reconstitute using sterile water (i.e.
The IL-3 protein is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. The PeproTech Recombinant Human IL-3 is a 15.
PeproTech Recombinant Human Activin A is a 26.0 kDa disulfide-linked homodimer of two beta-A chains, each containing 116 amino acid residues. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml.
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. PeproTech's E. coli-derived Human BMP-4 is a fully active homodimeric protein consisting of two 107 amino acid subunits, which correspond to amino acids 303-408 of...
The KGF (FGF-7) protein is one of 23 known members of the FGF family. PeproTech Recombinant Human KGF (FGF-7) is an 18.9 kDa protein consisting of 163 amino acid residues. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml.