Antibodies that detect GPR65 can be used in several scientific applications, including Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Immunohistochemistry (Frozen) and Flow Cytometry. These antibodies target GPR65 in Human, Rat and Mouse samples. Our GPR65 polyclonal antibodies are developed in Rabbit. Find the GPR65 antibody that fits your needs. Choose from 1 of 7 GPR65 antibodies, which have been validated in experiments with 11 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
GPR65 also known as TDAG8 is a transmembrane protein belonging to the G protein coupled receptor super family with 337-amino acid and 90% similarity and 81% identity in the 7 transmembrane domains of its mouse homolog. It has 3 potential N-linked glycosylation sites and is expressed predominantly in lymphoid organs and cancer tissues with increased expression during activation-induced death of T-cell hybridomas. Two major transcripts of 4.5 kb and 1.8 kb are found in peripheral blood leukocytes and functions as a novel proton-sensing receptor. It couples to adenylyl cyclase and psychosine and is also actively involved in the establishment of immunological autotolerance. GPR65 has a role in cellular transformation by RhoA activation and actin rearrangement under conditions accompanying tissue acidosis.