Antibodies that detect RADIL can be used in several scientific applications, including Immunocytochemistry, Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin) and Immunohistochemistry. These antibodies target RADIL in Human and Mouse samples. Our RADIL polyclonal antibodies are developed in Rabbit. Find the RADIL antibody that fits your needs. Choose from 1 of 3 RADIL antibodies, which have been validated in experiments with 12 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
Radil is a broadly expressed adapter protein that contains a RA-like domain, a PDZ domain and a DIL domain. Like RAPL and RIAM, Radil interacts preferentially with active GTP-bound Rap1, and overexpression of Radil enhances integrin-mediated adhesion. In addition, Radil knock down inhibits cell-substrate adhesion in HT1080, AD293, and NMuMG cells and results in migration defects in SW1353 and zebrafish neural crest cells. Radil regulates neutrophil adhesion by specifically enhancing beta2-integrin activation, as well as focal adhesion kinase (FAK) and paxillin phosphorylation.