Antibodies that detect TPCN2 can be used in several scientific applications, including Western Blot, Immunoprecipitation, ELISA, Immunohistochemistry and Immunohistochemistry (Frozen). These antibodies target TPCN2 in Human, Rat and Mouse samples. Our TPCN2 polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Relative expression to confirm specificity to TPCN2. Find the TPCN2 antibody that fits your needs. Choose from 1 of 8 TPCN2 antibodies, which have been validated in experiments with 8 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
Tpcn2 is a nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. Tpcn2 may also be involved in smooth muscle contraction. The Tpcn2 gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The Tpcn2 protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. Tpcn2 is a ubiquitously expressed gene that has elevated expression in liver and kidney. Two common nonsynonymous SNPs in the Tpcn2 gene strongly associate with blond versus brown hair pigmentation. Diseases associated with TPCN2 include Deafness, Autosomal Recessive 63 and Deafness, Autosomal Recessive 7.