Antibodies that detect LIF can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target LIF in Human, Mouse and Rat samples. Our LIF polyclonal, monoclonal and recombinant monoclonal...Antibodies that detect LIF can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target LIF in Human, Mouse and Rat samples. Our LIF polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse...Antibodies that detect LIF can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target LIF in Human, Mouse and Rat samples. Our LIF polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to LIF. Find the LIF antibody that fits your needs. Choose from 1 of 24 LIF antibodies, which have been validated in experiments with 14 publications and 81 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data...
Antibodies that detect LIF can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target LIF in Human, Mouse and Rat samples. Our LIF polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to LIF. Find the LIF antibody that fits your needs. Choose from 1 of 24 LIF antibodies, which have been validated in experiments with 14 publications and 81 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Leukemia inhibitory factor (LIF) is a 20 kDa protein that belongs to the IL-6 receptor family. It binds to a heterodimeric membrane receptor made up of a LIF-specific subunit, gp190 or LIFR, and the subunit gp130, which is shared with the other members of the IL-6 family. LIF expression has been observed in various tissues including thymus, lung, and neuronal tissue. LIF can be up-regulated by pro-inflammatory cytokines such as TNFα and IL-17, and elevated levels of LIF have been found in cases of rheumatoid arthritis, neural injury, systemic inflammation, and tuberculosis. LIF displays diverse biological effects, but is best known for its ability to inhibit the differentiation of embryonic stem cells in mice and contribute to stem cell self-renewal.Human and mouse LIF share 79% sequence homology and exhibit cross-species activity. However, LIF inhibition of stem cell differentiation appears to be mouse-specific.
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