Antibodies that detect ABRA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target ABRA1 in Human, Mouse, Rat and Non-human primate samples. Our ABRA1 polyclonal,...Antibodies that detect ABRA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target ABRA1 in Human, Mouse, Rat and Non-human primate samples. Our ABRA1 polyclonal, recombinant monoclonal and...Antibodies that detect ABRA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target ABRA1 in Human, Mouse, Rat and Non-human primate samples. Our ABRA1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown to confirm specificity to ABRA1. Find the ABRA1 antibody that fits your needs. Choose from 1 of 18 ABRA1 antibodies, which have been validated in experiments with 36 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced...
Antibodies that detect ABRA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target ABRA1 in Human, Mouse, Rat and Non-human primate samples. Our ABRA1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown to confirm specificity to ABRA1. Find the ABRA1 antibody that fits your needs. Choose from 1 of 18 ABRA1 antibodies, which have been validated in experiments with 36 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
CCDC98, also known as Abraxas 1, was identified through protein binding studies using the breast and ovarian predisposition protein BRCA1 as the binding target. CCDC98 recruits RAP80, a ubiquitin-binding protein, to BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both CCDC98 and RAP80 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either CCDC98 or RAP80 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that CCDC98 and RAP80 control only part of the DNA damage response role of BRCA1. At least two isoforms of CCDC98 are known to exist.
同义词
3830405G04Rik; 5630400M01Rik; ABRA1; abraxas protein; Abraxas1; AI506069; AL024423; AV118690; BRCA1-A complex subunit Abraxas; BRCA1-A complex subunit Abraxas 1; Ccdc98; coiled-coil domain containing 98; coiled-coil domain-containing protein 98; FAM175A; family with sequence similarity 175 member A; family with sequence similarity 175, member A; FLJ11520; FLJ12642; FLJ13614; Protein FAM175A; RGD1305287; UNQ496/PRO1013
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