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Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.
4,8-dimethylnonanoyl-CoA thioesterase; 48-dimethylnonanoyl-CoA thioesterase; ACOT8; ACTEIII; Acyl-CoA thioesterase 8; acyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; choloyl-coenzyme A thioesterase; hACTE-III; HIV-Nef associated acyl-CoA thioesterase; HIV-Nef-associated acyl-CoA thioesterase; HNAACTE; hTE; long-chain fatty-acyl-CoA hydrolase; NAP1; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; peroxisomal acyl-CoA thioesterase 2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; peroxisomal long-chain acyl-CoA thioesterase 1; PTE1; PTE-1; PTE2; PTE-2; Thioesterase II; thioesterase III
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