APS Antibodies

Antibodies that detect APS can be used in several scientific applications, including Immunohistochemistry, Immunocytochemistry, Western Blot and ELISA. These antibodies target APS in Human, Mouse and Rat samples. Our APS polyclonal antibodies are developed in Rabbit. Find the... Antibodies that detect APS can be used in several scientific applications, including Immunohistochemistry, Immunocytochemistry, Western Blot and ELISA. These antibodies target APS in Human, Mouse and Rat samples. Our APS polyclonal antibodies are developed in Rabbit. Find the APS antibody that fits your needs. Choose from 1 of 4... Antibodies that detect APS can be used in several scientific applications, including Immunohistochemistry, Immunocytochemistry, Western Blot and ELISA. These antibodies target APS in Human, Mouse and Rat samples. Our APS polyclonal antibodies are developed in Rabbit. Find the APS antibody that fits your needs. Choose from 1 of 4 APS antibodies, which have been validated in experiments with 2 publications and 6 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to... Antibodies that detect APS can be used in several scientific applications, including Immunohistochemistry, Immunocytochemistry, Western Blot and ELISA. These antibodies target APS in Human, Mouse and Rat samples. Our APS polyclonal antibodies are developed in Rabbit. Find the APS antibody that fits your needs. Choose from 1 of 4 APS antibodies, which have been validated in experiments with 2 publications and 6 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

APS (adapter protein with Pleckstrin homology and Src homology 2 domains) a member of the Lnk family, is an adaptor protein that is involved in B-cell signaling, insulin signaling, cytoskeletal reorganization. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B-cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK-STAT pathway in collaboration with c-Cbl. It is located in the cytoplasm in pre-PDGF (platelet derived growth factor) stimulated cells and localizes to the plasma membrane and peripheral regions upon PDGF stimulation. This protein is expressed in B-cells and mast cells when detected in haematopoietic cell lines yet is also expressed in many different tissues including spleen, prostrate, testis, uterus, small intestine and skeletal muscle.

同义词

adapter protein with pleckstrin homology and Src homology 2 domains; adaptor protein with pleckstrin homology and src homology 2 domains; Alpha-1-antitrypsin; Aps; SH2 and PH domain-containing adapter protein APS; SH2B adapter protein 2; SH2B adaptor protein 2; Sh2b2