Search Thermo Fisher Scientific
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
acetylcholine receptor; acetylcholine receptor, nicotinic, alpha 10 (neuronal); cholinergic receptor; cholinergic receptor nicotinic alpha 10 subunit; cholinergic receptor, nicotinic alpha 10; cholinergic receptor, nicotinic, alpha 10 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 10; Chrna10; NACHR alpha 10; NACHR alpha-10; NACHRA10; Neuronal acetylcholine receptor subunit alpha-10; neuronal nicotinic acetylcholine receptor subunit; nicotinic acetylcholine receptor subunit alpha 10; nicotinic acetylcholine receptor subunit alpha-10
100 µL
100 µL
100 µL
100 µL
100 µL
100 µL
100 µL