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Alomone Labs, LTD
Nicotinic Acetylcholine Receptor alpha 10 (CHRNA10) Polyclonal Antibody
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Nicotinic Acetylcholine Receptor alpha 10 (CHRNA10) Antibody (ANC-010-200UL) in WB
Western blot analysis of mouse brain lysates: - 1. Anti-Nicotinic Acetylcholine Receptor alpha 10 (CHRNA10) Antibody (#ANC-010), (1:400). 2. Anti-Nicotinic Acetylcholine Receptor alpha 10 (CHRNA10) Antibody , preincubated with Nicotinic Acetylcholine Receptor alpha 10/CHRNA10 Blocking Peptide (#BLP-NC010).
产品信息
ANC-010-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RRHEDWKRLARVMDR, corresponding to amino acid residues 411-425 of rat nAChR alpha 10, 2ndintracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; cholinergic receptor; cholinergic receptor, nicotinic, alpha polypeptide 10; NACHR alpha 10; NACHR alpha-10; Neuronal acetylcholine receptor subunit alpha-10; neuronal nicotinic acetylcholine receptor subunit; nicotinic acetylcholine receptor subunit alpha 10; Nicotinic acetylcholine receptor subunit alpha-10
基因别名: Chrna10
UniProt ID: (Rat) Q9JLB5
Entrez Gene ID: (Mouse) 504186, (Rat) 64574
