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Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
FMR1 autosomal homolog 2; FMR1L2; fragile X mental retardation gene 2, autosomal homolog; fragile X mental retardation syndrome-related protein 2; fragile X mental retardation, autosomal homolog 2; fragile X mental retardation-related protein 2; fragile X-mental retardation 1-like 2; Fxr2; Fxr2h; FXR2P
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