Antibodies that detect IL-31 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target IL-31 in Human, Mouse and Rat samples. Our IL-31 polyclonal, monoclonal, recombinant monoclonal...Antibodies that detect IL-31 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target IL-31 in Human, Mouse and Rat samples. Our IL-31 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal...Antibodies that detect IL-31 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target IL-31 in Human, Mouse and Rat samples. Our IL-31 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. Find the IL-31 antibody that fits your needs. Choose from 1 of 22 IL-31 antibodies, which have been validated in experiments with 9 publications and 48 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody...
Antibodies that detect IL-31 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target IL-31 in Human, Mouse and Rat samples. Our IL-31 polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. Find the IL-31 antibody that fits your needs. Choose from 1 of 22 IL-31 antibodies, which have been validated in experiments with 9 publications and 48 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
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