MC4R Antibodies

Antibodies that detect MC4R can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target MC4R in Human, Mouse, Rat, Non-human primate and Equine samples. Our MC4R... Antibodies that detect MC4R can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target MC4R in Human, Mouse, Rat, Non-human primate and Equine samples. Our MC4R polyclonal and recombinant monoclonal antibodies... Antibodies that detect MC4R can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target MC4R in Human, Mouse, Rat, Non-human primate and Equine samples. Our MC4R polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Alpaca. Find the MC4R antibody that fits your needs. Choose from 1 of 16 MC4R antibodies, which have been validated in experiments with 2 publications and 27 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the... Antibodies that detect MC4R can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target MC4R in Human, Mouse, Rat, Non-human primate and Equine samples. Our MC4R polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Alpaca. Find the MC4R antibody that fits your needs. Choose from 1 of 16 MC4R antibodies, which have been validated in experiments with 2 publications and 27 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

Expression of MC4R has been reported in brain. Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

同义词

MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

MC4R Antibodies

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