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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL27 encodes a 39S subunit protein.
39S ribosomal protein L27, mitochondrial; A630055F16Rik; D11Moh47; D18Ertd643e; HSPC250; L27mt; Mitochondrial large ribosomal subunit protein bL27m; mitochondrial ribosomal protein L27; Mrpl27; MRP-L27
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