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Antibody detects endogenous levels of total MRPL27.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL27 encodes a 39S subunit protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L27, mitochondrial; L27mt; Large ribosomal subunit protein bL27m; MRP-L27
基因别名: A630055F16Rik; D11Moh47; D18Ertd643e; HSPC250; L27mt; MRPL27
UniProt ID: (Human) Q9P0M9, (Mouse) Q99N92
Entrez Gene ID: (Human) 51264, (Mouse) 94064, (Rat) 287635
分子生物学功能: ribosomal protein