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NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.
AI573420; CHN; chondrosarcoma, extraskeletal myxoid, fused to EWS; CSMF; MINOR; mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; neuron-derived orphan receptor 1/2; Nor1; NOR-1; NOR-2; Nr4a3; Nuclear hormone receptor NOR-1; nuclear hormone receptor NOR-1/NOR-2; Nuclear receptor subfamily 4 group A member 3; nuclear receptor subfamily 4, group A, member 3; Orphan nuclear receptor TEC; TEC; TEC receptor; Translocated in extraskeletal chondrosarcoma
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