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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
BHLHE15; Class E basic helix-loop-helix protein 15; HMC13F06; HMC29C01; mSIM; SIM; SIM bHLH transcription factor 2; SIM transcription factor; sim2; single-minded 2; single-minded family bHLH transcription factor 2; single-minded homolog 2; single-minded homolog 2 (Drosophila); single-minded protein; transcription factor SIM2
100 µg
100 µL
100 µg
100 µL
100 µL
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