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Additional Information: This antibody is expected to recognize all reported isoforms (NP_005060.1; NP_033664.2).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: mSIM; SIM transcription factor; single-minded 2; Single-minded homolog 2
基因别名: bHLHe15; Sim2
UniProt ID: (Mouse) Q61079
Entrez Gene ID: (Mouse) 20465