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Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. [UniProt]
4930502N04Rik; A630020C16Rik; deubiquitinating enzyme 47; Trf (TATA binding protein-related factor)-proximal homolog; TRFP; Ubiquitin carboxyl-terminal hydrolase 47; ubiquitin specific peptidase 47; ubiquitin specific protease 47; ubiquitin thioesterase 47; ubiquitin thiolesterase 47; ubiquitin-specific-processing protease 47; Usp47
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