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Abnova
USP47 Monoclonal Antibody (5F9)
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产品信息
H00055031-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
5F9
抗原
USP47 (NP_060414, 203 a.a. approximately 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: TEQADLINEL YQGKLKDYVR CLECGYEGWR IDTYLDIPLV IRPYGSSQAF ASVEEALHAF IQPEILDGPN QYFCERCKKK CDARKGLRFL HFPYLLTLQ
靶标信息
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 47; Trf (TATA binding protein-related factor)-proximal homolog; Ubiquitin carboxyl-terminal hydrolase 47; Ubiquitin thioesterase 47; ubiquitin thiolesterase 47; Ubiquitin-specific-processing protease 47
基因别名: TRFP; USP47
UniProt ID: (Human) Q96K76
Entrez Gene ID: (Human) 55031
base-excision repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
negative regulation of G2/M transition of mitotic cell cycle
positive regulation of cell growth
cellular response to UV
monoubiquitinated protein deubiquitination
response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transcription, DNA-templated
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
