Product References
Neutrophil Extracellular Traps Release following Hypoxic-Ischemic Brain Injury in Newborn Rats Treated with Therapeutic Hypothermia.
International journal of molecular sciences
Bernis ME,Zweyer M,Maes E,Schleehuber Y,Sabir H
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri Feb 10 00:00:00 EST 2023
LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.
Journal for immunotherapy of cancer
Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
GPR84 regulates pulmonary inflammation by modulating neutrophil functions.
Acta pharmacologica Sinica
Wang SW,Zhang Q,Lu D,Fang YC,Yan XC,Chen J,Xia ZK,Yuan QT,Chen LH,Zhang YM,Nan FJ,Xie X
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
Role of Annexin A1 Secreted by Neutrophils in Melanoma Metastasis.
Cells
Sandri S,Hebeda CB,Broering MF,de Paula Silva M,Moredo LF,de Barros E Silva MJ,Sapata Molina A,Lopes Pinto CA,Duprat Neto JP,Reutelingsperger CP,Gil CD,Farsky SHP
16-9668-82 was used in Immunohistochemistry-immunofluorescence to show that AnxA1 secreted by neutrophils favors melanoma metastasis evolution via FPR pathways, addressing AnxA1 as a potential biomarker for the detection or progression of melanoma.
Fri Jan 27 00:00:00 EST 2023
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment.
Molecular therapy oncolytics
Tan Z,Chiu MS,Yan CW,Man K,Chen Z
16-9668-82 was used in Flow Cytometry to evaluate the potential of recombinant adeno-associated virus (rAAV)-vectored, PD1-based vaccination in the tumor microenvironment (TME) to activate antigen-specific T cell responses in the immune-competent murine mesothelioma model.
Fri Mar 26 00:00:00 EDT 2021
Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.
Muscle & nerve
Kawanishi N,Machida S
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Cell death & disease
Sun SN,Ni SH,Li Y,Liu X,Deng JP,Chen ZX,Li H,Feng WJ,Huang YS,Li DN,Xian SX,Yang ZQ,Wang LJ,Lu L
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology.
Vaccines
DeMarco JK,Royal JM,Severson WE,Gabbard JD,Hume S,Morton J,Swope K,Simpson CA,Shepherd JW,Bratcher B,Palmer KE,Pogue GP
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Wed Nov 17 00:00:00 EST 2021
CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology.
Vaccines
DeMarco JK,Royal JM,Severson WE,Gabbard JD,Hume S,Morton J,Swope K,Simpson CA,Shepherd JW,Bratcher B,Palmer KE,Pogue GP
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Wed Nov 17 00:00:00 EST 2021
Actin fence therapy with exogenous V12Rac1 protects against acute lung injury.
JCI insight
Gusarova GA,Das SR,Islam MN,Westphalen K,Jin G,Shmarakov IO,Li L,Bhattacharya S,Bhattacharya J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Mon Mar 22 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity.
Frontiers in immunology
Callejas BE,Blyth GAD,Jendzjowsky N,Wang A,Babbar A,Koro K,Wilson RJA,Kelly MM,Cobo ER,McKay DM
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri Dec 17 00:00:00 EST 2021
Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity.
Frontiers in immunology
Callejas BE,Blyth GAD,Jendzjowsky N,Wang A,Babbar A,Koro K,Wilson RJA,Kelly MM,Cobo ER,McKay DM
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri Dec 17 00:00:00 EST 2021
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer.
Journal for immunotherapy of cancer
Lee SJ,Yang H,Kim WR,Lee YS,Lee WS,Kong SJ,Lee HJ,Kim JH,Cheon J,Kang B,Chon HJ,Kim C
16-9668-82 was used in Flow Cytometry to elucidate the immune-evasion mechanisms during the peritoneal carcinomatosis of colon cancer and developed a novel immunotherapy by activating the stimulator of interferon genes (STING) pathway.
Tue Jun 01 00:00:00 EDT 2021
Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils.
Nature communications
Manriquez V,Nivoit P,Urbina T,Echenique-Rivera H,Melican K,Fernandez-Gerlinger MP,Flamant P,Schmitt T,Bruneval P,Obino D,Duménil G
16-9668-82 was used in Flow Cytometry to demonstrate how neutrophil recruitment contributes to resolution of Neisseria meningitidis in a humanized mouse model.
Tue Jul 27 00:00:00 EDT 2021
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Local sympathetic innervations modulate the lung innate immune responses.
Science advances
Liu T,Yang L,Han X,Ding X,Li J,Yang J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri May 01 00:00:00 EDT 2020
Local sympathetic innervations modulate the lung innate immune responses.
Science advances
Liu T,Yang L,Han X,Ding X,Li J,Yang J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri May 01 00:00:00 EDT 2020
Local sympathetic innervations modulate the lung innate immune responses.
Science advances
Liu T,Yang L,Han X,Ding X,Li J,Yang J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri May 01 00:00:00 EDT 2020
A Simple and Effective Flow Cytometry-Based Method for Identification and Quantification of Tissue Infiltrated Leukocyte Subpopulations in a Mouse Model of Peripheral Arterial Disease.
International journal of molecular sciences
Kumaraswami K,Salei N,Beck S,Rambichler S,Kluever AK,Lasch M,Richter L,Schraml BU,Deindl E
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry (PFA fixed)
Tue May 19 00:00:00 EDT 2020
A Simple and Effective Flow Cytometry-Based Method for Identification and Quantification of Tissue Infiltrated Leukocyte Subpopulations in a Mouse Model of Peripheral Arterial Disease.
International journal of molecular sciences
Kumaraswami K,Salei N,Beck S,Rambichler S,Kluever AK,Lasch M,Richter L,Schraml BU,Deindl E
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry (PFA fixed)
Tue May 19 00:00:00 EDT 2020
Neutrophil extracellular traps promote scar formation in post-epidural fibrosis.
NPJ Regenerative medicine
Jin Z,Sun J,Song Z,Chen K,Nicolas YSM,Kc R,Ma Q,Liu J,Zhang M
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunohistochemistry
Fri Oct 30 00:00:00 EDT 2020
IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A+Foxp3+ Cells During Mucosal Infection and Is Dysregulated With Aging.
Frontiers in immunology
Bhaskaran N,Faddoul F,Paes da Silva A,Jayaraman S,Schneider E,Mamileti P,Weinberg A,Pandiyan P
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses.
Science advances
Si Y,Tian Q,Zhao F,Kelly SH,Shores LS,Camacho DF,Sperling AI,Andrade MS,Collier JH,Chong AS
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.
Cells
Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Tue Jul 07 00:00:00 EDT 2020
Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection.
Nature microbiology
Rowe SE,Wagner NJ,Li L,Beam JE,Wilkinson AD,Radlinski LC,Zhang Q,Miao EA,Conlon BP
16-9668 was used in Immunohistochemistry to show that macrophages not only fail to efficiently kill phagocytosed Staphylococcus aureus, but also induce tolerance to multiple antibiotics.
Sat Feb 01 00:00:00 EST 2020
Antimesothelioma Immunotherapy by CTLA-4 Blockade Depends on Active PD1-Based TWIST1 Vaccination.
Molecular therapy oncolytics
Tan Z,Chiu MS,Yan CW,Wong YC,Huang H,Man K,Chen Z
16-9668-82 was used in Flow Cytometry to demonstrate that TWIST1, the basic helix-loop-helix transcription factor, was associated with human mesothelioma tumorigenesis and is required for the invasion and metastasis of mesothelioma in the immune-competent murine AB1 model.
Fri Mar 27 00:00:00 EDT 2020
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection.
Science advances
Park MY,Kim HS,Lee HY,Zabel BA,Bae YS
16-9668-82 was used in Flow Cytometry to find a previously unidentified pathogenic CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection with Staphylococcus aureus.
Wed Jan 01 00:00:00 EST 2020
Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.
Cell
Jin C,Lagoudas GK,Zhao C,Bullman S,Bhutkar A,Hu B,Ameh S,Sandel D,Liang XS,Mazzilli S,Whary MT,Meyerson M,Germain R,Blainey PC,Fox JG,Jacks T
16-9668-82 was used in Flow Cytometry to link local microbiota-immune crosstalk to lung tumor development and thereby define key cellular and molecular mediators that may serve as effective targets in lung cancer intervention.
Thu Feb 21 00:00:00 EST 2019
Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Blood
Albeituni S,Verbist KC,Tedrick PE,Tillman H,Picarsic J,Bassett R,Nichols KE
16-9668-82 was used in Flow Cytometry to show that ruxolitinib operates through IFN-γ-dependent and -independent mechanisms to dampen HLH by targeting the deleterious effects of T cells and neutrophils, with the latter representing an unappreciated and understudied cell type that contributes to HLH pathogenesis.
Thu Jul 11 00:00:00 EDT 2019
Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection.
Frontiers in immunology
Hiroki CH,Toller-Kawahisa JE,Fumagalli MJ,Colon DF,Figueiredo LTM,Fonseca BALD,Franca RFO,Cunha FQ
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunocytochemistry
Mon Nov 16 00:00:00 EST 2020
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
A phospholipase D2 inhibitor, CAY10594, ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
Scientific reports
Lee SK,Bae GH,Kim YS,Kim HS,Lee M,Ghim J,Zabel BA,Ryu SH,Bae YS
16-9668-82 was used in Flow Cytometry to investigate acetaminophen-induced acute liver injury treatment.
Fri May 10 00:00:00 EDT 2019
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells.
Journal for immunotherapy of cancer
Gao W,Zhang X,Yang W,Dou D,Zhang H,Tang Y,Zhong W,Meng J,Bai Y,Liu Y,Yang L,Chen S,Liu H,Yang C,Sun T
16-9668-82 was used in Flow Cytometry to investigate if a potential option for enhancing the efficacy of PD-1 inhibitors in clinical applications exists.
Wed Aug 28 00:00:00 EDT 2019
The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism.
Journal of immunology (Baltimore, Md. : 1950)
Fensterheim BA,Young JD,Luan L,Kleinbard RR,Stothers CL,Patil NK,McAtee-Pereira AG,Guo Y,Trenary I,Hernandez A,Fults JB,Williams DL,Sherwood ER,Bohannon JK
16-9668 was used in inhibition assays to demonstrate that MPLA prompts resistance to infection, in part, by inducing a sustained and dynamic metabolic program in macrophages.
Fri Jun 01 00:00:00 EDT 2018
Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production.
PLoS neglected tropical diseases
Dong B,Tong Z,Li R,Chen SC,Liu W,Liu W,Chen Y,Zhang X,Duan Y,Li D,Chen L
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis.
Nature communications
Rayes J,Lax S,Wichaiyo S,Watson SK,Di Y,Lombard S,Grygielska B,Smith SW,Skordilis K,Watson SP
16-9668 was used in Flow cytometry/Cell sorting to demonstrate, through two mouse models of sepsis, the anti-inflammatory role of the podoplanin-CLEC-2 axis.
Thu Dec 21 00:00:00 EST 2017
Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration.
Cell research
Cai Z,Zhang A,Choksi S,Li W,Li T,Zhang XM,Liu ZG
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE.
Basic research in cardiology
Tian Y,Pan D,Chordia MD,French BA,Kron IL,Yang Z
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Immunofluorescence
Tue Nov 01 00:00:00 EDT 2016
ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.
Frontiers in immunology
Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY
Published figure using Ly-6G monoclonal antibody (Product # 16-9668-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus.
PLoS pathogens
Kamenyeva O,Boularan C,Kabat J,Cheung GY,Cicala C,Yeh AJ,Chan JL,Periasamy S,Otto M,Kehrl JH
16-9668 was used in an ELISA assay to reveal that neutrophils mobilized from bone marrow after a bacterial challenge, dampen the early humoral response in the lymph node.
Wed Apr 01 00:00:00 EDT 2015