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Invitrogen
CD141 Recombinant Mouse Monoclonal Antibody (JAA17)
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FIGURE: 1 / 4
CD141 Antibody (740179M) in ICC/IF
Immunofluorescence analysis of CD141 was performed using CD141 Recombinant Mouse Monoclonal Antibody (JAA17) (Product # 740179M) on 70-80% confluent A-431 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, and then blocked with 2% BSA for 1 hour at room temperature. The cells were stained with CD141 Recombinant Mouse Monoclonal antibody (JAA17) (Product # 740179M, 1:800) in 0.1% BSA, incubated at 4 degree Celsius overnight, followed by labelling with Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alex... View More
Product Details
740179M
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
JAA17
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
Product Specific Information
Recombinant mouse monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Target Information
Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BDCA-3; CD141; CD141 antigen; DC141; Fetomodulin; sCD141; soluble CD141; Thrombomodulin; TM
Gene Aliases: AHUS6; BDCA3; CD141; THBD; THPH12; THRM; TM
UniProt ID: (Human) P07204
Entrez Gene ID: (Human) 7056
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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