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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QSPQRMNILN LDPSVALGFF CKEEKDFDNW CSLVQKEILK ENLRMFELVQ KHPSHWPPFV PPAKPEVTTT GAEFIDSTEQ LEEFDLEEDF EILSV
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 91%.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; ATG4 autophagy related 4 homolog A; AUT-like 2, cysteine endopeptidase; autophagin 2; autophagy 4 homolog A; autophagy related 4 homolog A; autophagy related 4A, cysteine peptidase-like 1; autophagy-related 4A; autophagy-related cysteine endopeptidase 2; autophagy-related protein 4 homolog A; cysteine protease APG4A; cysteine protease ATG4A-like; hAPG4A; MGC107179; unnamed protein product
基因别名: Agt4a; APG4A; Atg4al; Atg4al1; AUTL2; HsAPG4A; RGD1588268
UniProt ID: (Human) Q8WYN0, (Mouse) Q8C9S8
Entrez Gene ID: (Human) 115201, (Rat) 678769, (Mouse) 666468