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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
ATP6V0A1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adenosine triphosphatase; ATPase H+ transporting lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa); ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/116kD); ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa); ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1A (110/160 kDa); ATPase, H+ transporting, lysosomal noncatalytic accessory protein 1a; ATPase, H+ transporting, lysosomal V0 subunit a; Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit; V-A; V-ATPase 116 kDa; V-ATPase 116 kDa subunit a 1; V-ATPase a1; v-H+ATPase subunit a1; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a 1; V-type proton ATPase 116 kDa subunit a isoform 1; Vacuolar adenosine triphosphatase subunit Ac116; Vacuolar proton pump subunit 1; vacuolar proton translocating ATPase 116 kDa subunit a; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
基因别名: AA959968; ATP6a1; ATP6N1; ATP6N1A; ATP6V0A1; Atpv0a1; Vpp-1; VPP1
UniProt ID: (Mouse) Q9Z1G4, (Rat) P25286
Entrez Gene ID: (Mouse) 11975, (Rat) 29757