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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Actin Antibodies

          Invitrogen

          Actin Monoclonal Antibody (AC-40), FITC

          查看其他15个Actin抗体

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          Cite Actin Monoclonal Antibody (AC-40), FITC

          Actin Monoclonal Antibody (AC-40), FITC

          产品信息

          MA1-24908

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          Assay-dependent
          -

          免疫细胞化学 (ICC/IF)

          1:75
          -
          产品规格

          种属反应

          Dog, Chicken, Fish, Guinea pig, Goat, Hamster, Human, Mollusc, Mouse, Sheep, Pig, Rabbit, Reptile, Rat, Xenopus, Bovine

          宿主/亚型

          Mouse / IgG2a

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          AC-40

          抗原

          Synthetic actin C-terminal peptide Ser-Gly-Pro-Ser-Ile-Val-His-Arg-Lys-Cys-Phe, attached to a Multiple Antigen Peptide (MAP) backbone.
          查看免疫原

          偶联物

          FITC FITC FITC
          • Cyanine3
          • Request custom conjugation

          激发/发射光谱

          498/517 nm 查看光谱 spectra

          形式

          Liquid

          浓度

          2.9 mg/mL

          纯化类型

          purified

          保存液

          PBS, pH 7.4, with 1% BSA

          内含物

          15mM sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_779142

          产品详细信息

          Recommended positive controls: MDCK, human or chicken fibroblast.

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          靶标信息

          Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. In vertebrates there are three groups of actin isoforms: alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exists in most cell types as components of the cytoskeleton and as mediators of internal cell motility.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: a-actin; ACTB; actin; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin homolog; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; Actin, alpha cardiac muscle 1; Actin, alpha skeletal muscle; actin, alpha, cardiac 1; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; actin, beta; actin, beta, cytoplasmic; Actin, cytoplasmic 1; Actin, cytoplasmic 2; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; Actin, gamma-enteric smooth muscle; actin-like protein; alpha 1 skeletal muscle actin; alpha actin; alpha actin 1; alpha actin 2; Alpha-actin; alpha-actin cardiac; Alpha-actin-1; Alpha-actin-2; Alpha-actin-3; Alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; alphac-actin; Atcb; B-actin; Bact; actin; beta actin; beta cytoskeletal actin; Beta-actin; beta-actin FE-3; cardiac actin; cardiac muscle alpha actin 1; Cell growth-inhibiting gene 46 protein; cytoplasmic 1; cytoplasmic 2; cytoplasmic actin; Cytoplasmic beta-actin; cytoplasmic type 5; cytoskeletal beta actin; cytoskeletal gamma-actin; cytoskeletal protein; deafness, autosomal dominant 20; deafness, autosomal dominant 26; epididymis luminal protein 176; gamma 1 propeptide; gamma non-muscle actin; Gamma-2-actin; Gamma-actin; gamma-enteric smooth muscle actin; nemaline myopathy type 3; pan actin; PS1TP5-binding protein 1; RP5-1068B5.2; skeletal alpha actin; smooth muscle alpha-actin; Smooth muscle gamma-actin; type 5; unnamed protein product; vascular smooth muscle alpha-actin

          查看更多 收起

          基因别名: 0610041G09Rik; a-SMA; AA959943; AAT6; ACT; ACT-4; ACT-5; Act4; ACTA; Acta-2; ACTA1; ACTA2; ACTA3; ACTB; ACTC; Actc-1; ACTC1; ACTE; ACTG; ACTG1; ACTG2; ACTGE; actin; Actl; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; ACTVS; Actx; AL023024; alphaSMA; ASD5; ASMA; Bact; Beta-actin; BRWS1; BRWS2; CFTD; CFTD1; CFTDM; CMD1R; CMH11; DFNA20; DFNA26; E430023M04Rik; E51; GAMMA-ACTIN; GIG46; HEL-176; I79_002310; I79_013242; I79_019066; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; PS1TP5BP1; SHPM; SMalphaA; SMGA; VSCM; XELAEV_18029136mg; XELAEV_18045052mg

          查看更多 收起

          UniProt ID: (Human) P68133, (Bovine) P68138, (Pig) P68137, (Bovine) P62739, (Human) P62736, (Rabbit) P62740, (Chicken) P08023, (Pig) Q6QAQ1, (Human) P60709, (Chicken) P60706, (Dog) O18840, (Rabbit) P29751, (Bovine) P60712, (Sheep) P60713, (Chicken) P04270, (Human) P68032, (Bovine) Q3ZC07, (Chicken) P53478, (Bovine) P63258, (Human) P63261, (Bovine) Q5E9B5, (Human) P63267, (Chicken) P63270, (Mouse) P68134, (Rat) P68136, (Mouse) P62737, (Rat) P62738, (Rat) P60711, (Guinea pig) Q71FK5, (Mouse) P60710, (Chinese hamster) P48975, (Rat) P68035, (Mouse) P68033, (Rat) P63259, (Mouse) P63260, (Mouse) P63268, (Rat) P63269, (Xenopus) O93400

          查看更多 收起

          Entrez Gene ID: (Rabbit) 100009506, (Sheep) 101107662, (Goat) 102182476, (Chicken) 421534, (Human) 58, (Bovine) 281592, (Pig) 100154254, (Dog) 488984, (Pig) 733615, (Goat) 102191486, (Bovine) 515610, (Human) 59, (Dog) 477587, (Rabbit) 100009271, (Chicken) 423787, (Sheep) 101121051, (Pig) 414396, (Human) 60, (Chicken) 396526, (Dog) 403580, (Rabbit) 100009272, (Bovine) 280979, (Sheep) 443052, (Goat) 102179831, (Dog) 478250, (Chicken) 423298, (Sheep) 101111554, (Pig) 100152267, (Human) 70, (Bovine) 533219, (Goat) 102170606, (Rabbit) 100340339, (Goat) 100860883, (Chicken) 415296, (Bovine) 404122, (Pig) 397653, (Sheep) 443340, (Human) 71, (Dog) 475923, (Goat) 102178279, (Bovine) 281595, (Human) 72, (Dog) 475792, (Sheep) 101114256, (Chicken) 396084, (Pig) 100520667, (Rabbit) 100350318, (Chinese hamster) 100768972, (Mouse) 11459, (Guinea pig) 100716933, (Rat) 29437, (Mouse) 11475, (Rat) 81633, (Chinese hamster) 100758575, (Guinea pig) 100722917, (Rat) 81822, (Guinea pig) 100135470, (Mouse) 11461, (Chinese hamster) 100689477, (Rat) 29275, (Guinea pig) 100731953, (Mouse) 11464, (Chinese hamster) 100766388, (Chinese hamster) 100764022, (Rat) 287876, (Mouse) 11465, (Guinea pig) 100731713, (Mouse) 11468, (Chinese hamster) 100768744, (Guinea pig) 100716255, (Rat) 25365, (Xenopus) 432314, (Xenopus) 398459

          查看更多 收起

          功能
          protein binding ATP binding structural constituent of cytoskeleton myosin binding ADP binding protein kinase binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding kinesin binding Tat protein binding nucleosomal DNA binding identical protein binding nitric-oxide synthase binding structural constituent of postsynaptic actin cytoskeleton ATPase activity profilin binding ubiquitin protein ligase binding nucleotide binding molecular_function actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein
          参与通路
          skeletal muscle thin filament assembly skeletal muscle fiber development muscle contraction response to mechanical stimulus response to extracellular stimulus response to lithium ion positive regulation of gene expression cell growth muscle filament sliding skeletal muscle fiber adaptation response to steroid hormone mesenchyme migration regulation of blood pressure response to virus vascular smooth muscle contraction glomerular mesangial cell development postsynaptic actin cytoskeleton organization retina homeostasis movement of cell or subcellular component cytoskeleton organization substantia nigra development cell junction assembly Fc-gamma receptor signaling pathway involved in phagocytosis ATP-dependent chromatin remodeling positive regulation of gene expression, epigenetic vascular endothelial growth factor receptor signaling pathway ephrin receptor signaling pathway platelet aggregation axonogenesis cell motility morphogenesis of a polarized epithelium establishment or maintenance of cell polarity regulation of transmembrane transporter activity negative regulation of protein binding adherens junction assembly apical protein localization synaptic vesicle endocytosis regulation of norepinephrine uptake protein localization to adherens junction cellular response to cytochalasin B regulation of protein localization to plasma membrane actin filament organization actin-myosin filament sliding heart contraction apoptotic process actin filament-based movement actomyosin structure organization response to drug negative regulation of apoptotic process response to ethanol cardiac myofibril assembly cardiac muscle tissue morphogenesis cardiac muscle contraction angiogenesis positive regulation of cell migration regulation of stress fiber assembly regulation of focal adhesion assembly positive regulation of wound healing tight junction assembly protein localization to bicellular tight junction sarcomere organization retina development in camera-type eye cellular response to electrical stimulus metabolic process actin-mediated cell contraction response to calcium ion biological_process
          It has to be done as per old AB suggested Products section.
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