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Invitrogen
CGRP Recombinant Rabbit Monoclonal Antibody (BLR159J)
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产品信息
MA5-44503
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
BLR159J
抗原
Peptide representing a region between residue 75 and 125 of mouse Calcitonin gene-related Peptide 1.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
purified
保存液
BBS, pH 7.8-8.6, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
靶标信息
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-type CGRP; Calcitonin; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; CGRP-I; CGRP1; MGC126648; RAT calcitonin
基因别名: CA; Calc; Calc1; Calca; Cgrp; CGRP-1; CGRP1; Ct; Ctn
UniProt ID: (Mouse) P70160
Entrez Gene ID: (Mouse) 12310
neurological system process involved in regulation of systemic arterial blood pressure
vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
regulation of heart rate
cellular calcium ion homeostasis
inflammatory response
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
neuropeptide signaling pathway
neuromuscular junction development
feeding behavior
regulation of heart contraction
regulation of blood pressure
response to heat
negative regulation of ossification
negative regulation of neurological system process
vasodilation
negative regulation of blood pressure
positive regulation of ossification
positive regulation of cell adhesion
negative regulation of smooth muscle contraction
sperm capacitation
response to pain
detection of temperature stimulus involved in sensory perception of pain
mitophagy in response to mitochondrial depolarization
cellular response to nerve growth factor stimulus
