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This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
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CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Charged multivesicular body protein 2b; CHMP family; CHMP2.5; CHMP2b; chromatin modifying protein 2B; Chromatin-modifying protein 2b; hVps2-2; Vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; Vps2-2
基因别名: 1190006E07Rik; ALS17; CGI-84; CHMP2.5; CHMP2B; DMT1; RGD1306781; VPS2-2; VPS2B
UniProt ID: (Human) Q9UQN3, (Mouse) Q80UZ4
Entrez Gene ID: (Human) 25978, (Mouse) 68942, (Rat) 363720
分子生物学功能: membrane traffic protein