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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MHNAEYDVLH APPADDRDQS SMEDGEDTPV TKLQR
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
DENND5A (DENN domain-containing protein 5A) is a guanine nucleotide exchange factor (GEF) which activates RAB6A and RAB39A/RAB39B. It promotes the exchange of GDP to GTP by converting inactive GDP-bound Rab proteins to their active GTP form. DENND5A is also involved in the negative regulation of neurtie outgrowth. Mutations affecting this gene can result in epileptic encephalopathy, early infantile, 49 (EIEE49).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DENN domain-containing protein 5A; Rab6-interacting protein 1; Rab6IP1
基因别名: DENND5A; KIAA1091; RAB6IP1
Entrez Gene ID: (Human) 23258