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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RSWEEHVTHW MGQPFNSDDR NTACHHGLVA DSLQASMEKD ATLNVDRKEK CVSLPDCCHG SELRDFPGRP MGHLSKDVDE NDSHEGEDQF LSLEASTETL VHVSDEDNNA DLCLTDDKQV LNTQGQ
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 22%.
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ARHGAP 7; Deleted in liver cancer 1 protein; DLC 1; DLC-1; FLJ21120; HP protein; p122 RhoGAP; Rho GTPase-activating protein 7; Rho-type GTPase-activating protein 7; StAR-related lipid; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain-containing protein 12; transfer protein 12
基因别名: ARHGAP7; DLC1; KIAA1723; STARD12
Entrez Gene ID: (Human) 10395