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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAVKLGTLLL ALALGLAQPA SARRKLLVFL LDGFRSDYIS DEALESLPGF KEIVSRGVKV DYLTPDFPSL SYPNYYTLMT GRHCEVHQMI GNYMWDPTTN KSFDIGVNKD SLMPLWWNGS EPLWVTLTKA KRKVYMYYWP GCEVEILGVR PTYCLEYKNV PTDINFANAV SDALDSFKSG RADLAAIYHE RIDVEGHHYG PASPQRKDAL KAVDTVLKYM TKWIQERGLQ DRLNVIIFSD HGMTDIFWMD KVIELNKYIS LNDLQQVKDR GPVVSLWPAP GKHSEIYNKL STVEHMTVYE KEAIPSRFYY KKGKFVSPLT LVADEGWFIT ENREMLPFWM NSTGRREGWQ RGWHGYDNEL MDMRGIFLAF GPDFKSNFRA APIRSVDVYN VMCNVVGITP LPNNGSWSRV MCMLKGRAST APPVWPSHCA LALILLFLLA
Choline-specific glycerophosphodiester phosphodiesterase. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B830047L21Rik; choline-specific glycerophosphodiester phosphodiesterase; E-NPP 6; ectonucleotide pyrophosphatase/phosphodiesterase family member 6; GPC-Cpde; NPP-6; unnamed protein product
基因别名: NPP6
UniProt ID: (Human) Q6UWR7
Entrez Gene ID: (Human) 133121