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Invitrogen
FBXW2 Polyclonal Antibody
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产品信息
PA5-18189
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KRGSSFLAGEHPG) corresponding to the C-terminus amino acids of FBXW2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, canine and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
靶标信息
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; F-box and WD-40 domain-containing protein 2 {ECO:0000312|EMBL:AAI66990.1}; F-box protein Fbw2; F-box/WD repeat-containing protein 2; fbxw2 {ECO:0000312|RGD:1310460}; MGC117371; Protein MD6
基因别名: 2700071L08Rik; FBW2; FBXW2; FWD2; MD6
UniProt ID: (Human) Q9UKT8, (Rat) B2RZ17
Entrez Gene ID: (Human) 26190, (Rat) 311881, (Mouse) 30050
