Search
Invitrogen
FXR1 Recombinant Rabbit Monoclonal Antibody (9D20)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 16
FXR1 Antibody (MA573169) in ICC/IF
Immunocytochemistry analysis of FXR1 in MCF-7 cells. Permeabilized with Trinton X-100 at room temp for 20 min. Samples were incubated with FXR1 Recombinant Monoclonal (Product # MA573169 using a dilution at 1:100, for 90 min at 37°C. Followed by conjugated Goat Anti-Rabbit IgG antibody (green) at 37°C for 90 min, DAPI was used to stain the cell nuclei. PBS instead of the primary antibody was used as the blank control.
产品信息
MA573169
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9D20
抗原
KLH conjugated synthetic peptide derived from human FXR1.
偶联物
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: FMR1 autosomal homolog 1; FMR1 autosomal protein-like protein 1; fragile X mental retardation gene, autosomal homolog; fragile X mental retardation syndrome-related protein 1; fragile X mental retardation-related protein 1; fragile-X-related protein 1; FXR1P; hFXR1p; mFxr1p; RNA-binding protein FXR1; unnamed protein product
基因别名: 1110050J02Rik; 9530073J07Rik; AI851072; CMYO9A; CMYO9B; CMYP9A; CMYP9B; FXR1; Fxr1h; FXR1P; MYOPMIL; MYORIBF
UniProt ID: (Human) P51114, (Rat) Q5XI81, (Mouse) Q61584
Entrez Gene ID: (Human) 8087, (Rat) 361927, (Mouse) 14359
nucleic acid binding
RNA binding
mRNA binding
mRNA 3'-UTR binding
protein binding
RNA strand annealing activity
mRNA 3'-UTR AU-rich region binding
protein homodimerization activity
ribonucleoprotein complex binding
translation regulator activity
protein heterodimerization activity
molecular condensate scaffold activity
G-quadruplex RNA binding
poly(A) RNA binding
translation factor
cytoplasmic translational initiation
regulation of translation
apoptotic process
spermatogenesis
spermatid development
muscle organ development
posttranscriptional regulation of gene expression
negative regulation of translation
dentate gyrus development
cell differentiation
negative regulation of tumor necrosis factor production
positive regulation of Rho protein signal transduction
regulation of mRNA stability
regulation of circadian sleep/wake cycle, sleep
positive regulation of translation
positive regulation of long-term neuronal synaptic plasticity
animal organ development
negative regulation of inflammatory response
regulation of neurogenesis
mRNA transport
nuclear pore complex assembly
nuclear pore localization
regulation of synaptic transmission, glutamatergic
skeletal muscle organ development
muscle structure development
mRNA destabilization
regulation of translation at presynapse, modulating synaptic transmission
membraneless organelle assembly
negative regulation of long-term synaptic potentiation
negative regulation of mRNA catabolic process
positive regulation of gene silencing by miRNA
multicellular organism development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
