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Invitrogen
G6PC Polyclonal Antibody
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Product Details
PA5-100249
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human G6PC(Accession P35575), corresponding to amino acid residues G68-G118.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total G6PC.
Target Information
Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-6-Pase; G6Pase-alpha; Glucose-6-phosphatase; Glucose-6-phosphatase alpha; Glucose-6-phosphatase catalytic subunit 1; glucose-6-phosphatase, catalytic subunit; MGC163350
Gene Aliases: G6Pase; G6PC; G6PC1; G6PT; GSD1; GSD1a
UniProt ID: (Human) P35575
Entrez Gene ID: (Human) 2538
glycogen metabolic process
glycogen catabolic process
gluconeogenesis
triglyceride metabolic process
steroid metabolic process
regulation of gene expression
glucose transport
glucose-6-phosphate transport
response to food
multicellular organism growth
glucose homeostasis
cholesterol homeostasis
urate metabolic process
phosphorylated carbohydrate dephosphorylation
glucose 6-phosphate metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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