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Abnova
GGA1 Polyclonal Antibody, MaxPab™
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GGA1 Antibody (H00026088-D01P) in WB
Western Blot analysis of GGA1 expression in transfected 293T cell line (H00026088-T02) by GGA1 MaxPab polyclonal antibody.
Lane 1: GGA1 transfected lysate(61.40 KDa).
Lane 2: Non-transfected lysate.
Lane 1: GGA1 transfected lysate(61.40 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00026088-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GGA1 (NP_001001560.1, 1 a.a. approximately 552 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEPAMEPETL EARINRATNP LNKELDWASI NGFCEQLNED FEGPPLATRL LAHKIQSPQE WEAIQALTVL ETCMKSCGKR FHDEVGKFRF LNELIKVVSP KYLGSRTSEK VKNKILELLY SWTVGLPEEV KIAEAYQMLK KQGIVKSDPK LPDDTTFPLP PPRPKNVIFE DEEKSKMLAR LLKSSHPEDL RAANKLIKEM VQEDQKRMEK ISKRVNAIEE VNNNVKLLTE MVMSHSQGGA AAGSSEDLMK ELYQRCERMR PTLFRLASDT EDNDEALGLS DPTPPSGPSL DGTGWNSFQS SDATEPPAPA LAQAPSMESR PPAQTSLPAS SGLDDLDLLG KTLLQQSLPP ESQQVRWEKQ QPTPRLTLRD LQNKSSSCSS PSSSATSLLH TVSPEPPRPP QQPVPTELSL ASITVPLESI KPSNILPVTV YDQHGFRILF HFARDPLPGR SDVLVVVVSM LSTAPQPIRN IVFQSAVPKV MKVKLQPPSG TELPAFNPIV HPSAITQVLL LANPQKEKVR LRYKLTFTMG DQTYNEMGDV DQFPPPETWG SL
靶标信息
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor binding protein 1; ADP-ribosylation factor-binding protein GGA1; gamma-adaptin related protein 1; Gamma-adaptin-related protein 1; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; Golgi-localized, gamma ear-containing, ARF-binding protein 1
基因别名: GGA1
UniProt ID: (Human) Q9UJY5
Entrez Gene ID: (Human) 26088
