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Abnova
GGA1 Monoclonal Antibody (1G8)
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GGA1 Antibody (H00026088-M02) in WB
Western blot analysis of GGA1 over-expressed 293 cell line, cotransfected with GGA1 Validated Chimera RNAi (Cat # H00026088-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with GGA1 monoclonal antibody (M02), clone 1G8 (Cat # H00026088-M02). GAPDH ( 36.1 kDa ) used as specificity and loading control.
产品信息
H00026088-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1G8
抗原
GGA1 (AAH29388, 1 a.a. approximately 89 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEPAMEPETL EARINRATNP LNKELDWASI NGFCEQLNED FEGPPLATRL LAHKIQSPQE WEAIQALTVR RGEATIRPPP CDDTKGGQD
靶标信息
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor binding protein 1; ADP-ribosylation factor-binding protein GGA1; gamma-adaptin related protein 1; Gamma-adaptin-related protein 1; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; Golgi-localized, gamma ear-containing, ARF-binding protein 1
基因别名: GGA1
UniProt ID: (Human) Q9UJY5
Entrez Gene ID: (Human) 26088
