Invitrogen

HLA-ABC Monoclonal Antibody (W6/32), PE

Name: HLA-ABC Monoclonal Antibody (W6\/32), PE
Brand: Invitrogen
SKU: MA1-19662

4 篇参考文献

查看其他62个HLA-ABC抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

HLA-ABC Antibody in Flow Cytometry (Flow)

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HLA-ABC Antibody (MA1-19662) in Flow

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-HLA-class I (W6/32) PE Monoclonal antibody (Product # MA1-19662).

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Immunogen image

Immunogen Image HLA-ABC Monoclonal Antibody (W6/32), PE

产品信息

MA1-19662

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

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流式细胞分析 (Flow)

1-5 µg/mL

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产品规格

种属反应

Bovine, Cat, Human, Non-human primate

已发表种属

Human

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

W6/32

抗原

Membrane of human tonsil cells.

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偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Liquid

浓度

0.1 mg/mL

100 µg

纯化类型

Size-exclusion chromatography

保存液

PBS, pH 7.4, with 0.2% BSA

内含物

15mM sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_1076693

产品详细信息

This antibody recognizes an extracellular epitope of MHC Class I molecules (MHC Class Ia) that are expressed on the surface of all human nucleated cell types. The antibody W6/32 is a valuable reagent for analyzing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody W6/32 is also suitable as a positive control for HLA tissue typing and crossmatching.

This antibody will not cross-react with rabbit.

靶标信息

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

生物信息学

蛋白别名: allele B-3515; B*3509; cell surface glycoprotein; integral membrane protein; exons 2-8; glycosylation aa 86, alpha domain 1 aa 1-24, alpha domain 2 aa 25-114, alpha domain 3 aa 207-298; glycosylation aa 86, alpha domain 1 aa 25-114, alpha domain 2 aa 115-206, alpha domain 3 aa 207-298; H-2K; H-2K(d); H2-K; heavy chain; hla antigen; HLA B-1519; HLA class I antigen HLA-B; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA protein allele A25; HLA protein allele B37; HLA protein allele B51; HLA protein allele B57; HLA protein allele B7; HLA-A; HLA-A 2402; HLA-A*0201 alpha chain; human leukocyte antigen; HLA-A*0204; HLA-A*0207 alpha chain; human leukocyte antigen; HLA-A-0102 allele; HLA-A24AK; HLA-A25; HLA-B; HLA-B 1502; HLA-B*4002; HLA-B-07ZEL allele; HLA-B-1501; HLA-B-1516; HLA-B-1520 allele; HLA-B-15AOH allele; HLA-B-15ZEL allele; HLA-B-27KSH allele; HLA-B-67LAV allele; This submission reports an HLA-B-6701 variant (HLA-B-67LAV) that differs from the published B-6701 sequence, GenBank Accession Number L17005; HLA-B18; HLA-B27 peptide; HLA-B39; HLA-B41 variant; HLA-B61; HLA-Bw-39-DBU allele; HLA-C; HLA-C antigen; HLA-Cw; HLA-Cw1 protein; HLA-Cw2 protein; HLA-Cw3 protein; human leukocyte antigen; Human leukocyte antigen A; Human leukocyte antigen B; Human leukocyte antigen C; human leukocyte antigen-C alpha chain; leucocyte antigen A; leukocyte antigen class I-A; leukocyte antigen class I-B; lymphocyte antigen; major histocompatibility antigen HLA-C; major histocompatibility complex class I A; major histocompatibility HLA-Cw2.2 heavy chain; MGC184092; MGC7052; MHC 1; MHC Class 1; MHC class 1 antigen; MHC class I; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen SHCHA; MHC class I molecule; MHC class I-like alpha chain membrane-bound type; MHC HLA-A cell surface antigen; MHC HLA-A10-alpha-2 chain precursor; MHC HLA-A2.4a chain; MHC HLA-A24 cell surface glycoprotein; MHC HLA-ABC; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B44; MHC HLA-B7 heavy chain precursor; MHC HLA-Bw46; MHC HLA-C-alpha-2 chain precursor; MHC I HLA; MHC1; similar to Homo sapiens MHC HLA-B39 mRNA with GenBank Accession Number L42024.1; subtype B*3508 differs at residue 156 (Leu->Arg) with subtype B*3501; unnamed protein product

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基因别名: AS; B-4901; D6S204; HLA-A; HLA-B; HLA-C; HLA-JY3; HLAA; HLAB; HLAC; HLC-C; MHC; PSORS1

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UniProt ID: (Human) P04439, (Human) P01889, (Human) P10321

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Entrez Gene ID: (Human) 3105, (Human) 3106, (Human) 3107

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