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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive test controls include: NIH/3T3, 293T, BT-474. The target is usually found in the following locations: Cytoplasm, Nucleus.
Immunogen sequence: MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp781N0678; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMP dehydrogenase type 1 (EC 1.1.1.205); IMPD 1; IMPDH 1; inosine 5'-phosphate dehydrogenase 1; unnamed protein product
基因别名: B930086D20Rik; IMPD; IMPD 1; IMPD1; IMPDH 1; IMPDH-I; LCA11; RP10; sWSS2608
UniProt ID: (Human) P20839, (Mouse) P50096, (Rat) D3ZLZ7
Entrez Gene ID: (Human) 3614, (Mouse) 23917, (Rat) 362329