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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Keep as concentrated solution.
Predicted reactivity: Mouse (91%), Rat (91%), Xenopus laevis (83%), Chicken (87%), Bovine (96%).
Positive Control: HeLa, MDA-MB-231, U87-MG, SK-N-SH, SK-N-AS, 293T transfected with LOXL2, mouse lung.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Lysyl oxidase homolog 2; Lysyl oxidase-like protein 2; Lysyl oxidase-related protein 2; Lysyl oxidase-related protein WS9-14
基因别名: LOXL2
Entrez Gene ID: (Human) 4017