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Invitrogen
MTGR1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-97543
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Protein CBFA2T2 protein (325-604AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CBFA2/RUNX1 translocation partner 2; core-binding factor, runt domain, alpha subunit 2; translocated to, 2; DKFZp313F2116; ETO homolog on chromosome 20; ETO homologous on chromosome 20; MTG8-like protein; MTG8-related protein 1; myeloid translocation gene-related protein 1; Myeloid translocation-related protein 1; p85; Protein CBFA2T2; RP5-1137F22.1; unnamed protein product; ZMYND3 CBFA2T2
基因别名: CBFA2T2; EHT; MTGR1; p85; ZMYND3
UniProt ID: (Human) O43439
Entrez Gene ID: (Human) 9139
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
positive regulation of neuron projection development
negative regulation of neuron projection development
epithelial cell differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
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